LOWELL -- When UMass Lowell police were dispatched to the 11th floor of Fox Hall Sunday night, they found student Colin Bost, who was agitated, acting strangely and appeared to be under the influence of something.

When asked if he had taken any drugs, the student became aggressive and had to be sprayed with a chemical spray to be subdued.

After he was handcuffed, Bost began to scream "yellow, blue, yellow.'' Four residents of Fox Hall told police that before police arrived, Bost had allegedly accosted several female students.

Bost's friend allegedly told police that Bost had been taking a new designer drug called "251," a form of LSD also known as "smiles."

Lowell police spokesman Kelly Richardson said this is the first time he has heard of this new designer drug.

Lowell Health Inspector Frank Singleton said this is the first case of "251" in Lowell that he has heard of, but the drug has been around since 2010 and has gone nationwide.

While there are few overdoses with this kind of drug, Singleton warns that these drugs are very dangerous and can have psychological side effects.

After his arrest, Bost was transported to Lowell General Hospital. When questioned at the hospital, Bost allegedly admitted he took "251," which he got from another student, court documents state.

After taking a tab of "251," Bost told police his "mind goes blank," according to court documents. He apologized for his actions, documents state.

In Lowell District Court on Monday, Bost, 18, of Beaverton, Ore.


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, pleaded not guilty to charges of assault and battery on a police officer, disorderly conduct and resisting arrest.

He was released on personal recognizance with conditions that he consume no drugs or alcohol.

His next court date is March 17 for a pretrial conference.

Neither Bost nor his attorney could be reached for comment.

UMass Lowell spokesperson Christine Gillette said, "This is the only incident the university has seen reportedly involving this drug.''

She added that from orientation through graduation, students participate in programs addressing the dangers of all such substances and the importance of good decision-making, and there is ongoing communication with student affairs and other staff that provide opportunities to discuss these topics.

The drug is derived from mescaline, but has a different chemical compound. Sold primarily on the Internet, it usually comes in powder form, although users typically take the drug by ingesting blotter paper soaked with the liquid.

The chemicals in synthetic drugs produce a high that mimics other drugs. Bath salts, for example, are supposed to produce a high like cocaine or methamphetamine, while the newer "251" is a hallucinogenic, like LSD, according to published reports.

The drug, sometimes also called "N-Bomb" for its chemical compositions, 2C-1-NBOMe or 251NBOMe, can be extremely potent and dangerous, according to published reports. Deaths have been reported in North Dakota, Virginia, Louisiana and Arizona. Users also have to worry about long-term damage to kidneys and possibly kidney disorders, as well as mental disorders.

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