ST. PETERSBURG, Fla. (AP) -- Rookie Mookie Betts hit his first career grand slam, Anthony Ranaudo pitched six effective innings and the Boston Red Sox beat the Tampa Bay Rays, 8-4, Friday night.

Sox 8, Rays 4

After Yoenis Cespedes drove in his second run of the game with a double, Betts connected off Chris Archer (8-7) to cap a five-run second inning that made it 8-0.

Ranaudo (3-0), recalled from Triple-A Pawtucket before the game, gave up three runs and five hits.

Archer allowed eight runs and nine hits over four innings.

There were no incidents in the first meeting between the teams since Archer and the Rays took issue with the way David Ortiz acted after hitting a three-run homer off the Tampa Bay pitcher on July 27.

Ortiz singled in five at-bats.

Cespedes and Daniel Nava each hit RBI singles during a three-run first. The other run scored on one of two Tampa Bay errors in the inning. The Rays have at least one error in six consecutive games.