BOSTON (AP) -- Massachusetts House Speaker Robert DeLeo and Senate President Therese Murray are calling for the Department of Children and Families commissioner to resign, citing a lack of leadership at the child welfare agency.

The two top Democrats said Olga Roche should step down following the recent deaths of two children, one over the weekend.

Democratic Gov. Deval Patrick, who has defended Roche, said Monday he no longer has confidence in the agency.

Authorities say the family of a 2-week old Fitchburg baby who died over the weekend was being monitored by state child welfare officials.

In the second case, a DCF spokeswoman says a fax from Grafton police about possible harm to a 4-week-old who later died was misplaced for six days. DCF said it's saddened by the death and is reviewing its policies regarding reports received via fax.